Obesity paradox
نویسندگان
چکیده
Several studies verify and emphasize the obesity paradox but they do not offer any evident explanation for the paradox. Obesity paradox explanation by pathogenetic action mechanisms of parathyroid hormone-related protein and calcitonin gene-related peptide is evaluated. The vasodilatant action of these peptides has been taken into consideration in decreasing the peripheral arterial vascular tone during obesity in response to the obesity-increased renin-angiotensin-aldosterone and sympathetic system activity.
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